Micronutrients in the prevention of osteoporosis
By increasing levels of health care, older people make up more of the community, and osteoporosis is of importance paramount as part of the elder disease, as it affects the quality of life of these people and imposes high health costs of society.
Osteoporosis or osteoporosis is a multifactorial disease and is one of the major health problems in developed and developing countries. Getting insufficient calcium and micronutrients in a diet during childhood and adolescence may lead to an outbreak in adulthood. Getting inadequate nutrients can increase your risk of losing weight and gaining osteoporosis. Foods like calcium and vitamin DAnd also micronutrients such as copper, zinc and magnesium are effective factors in the trachea. Osteoporosis is also considered as one of the diseases associated with mineral deficiencies along with other diseases. Considering the water content of our country, which contains low amounts of micronutrients, it seems that the deficiency of some formic elements may be among the causes of osteoporosis.
The definition of osteoporosis by Consensus Development Conference was to have been parameters:
• reduce Bone mass
• Disorganization of bone mass micro architectural leading the risk of fractures.
Based on the WHO criteria (World Health Organization), osteoporosis is considered to be practical in terms of reduction of tracheal intakes of 2.5 standard deviations below the mean for healthy and young adults with the same sex and gender (-BMD <5/2).
If the trachea is less than 2.5 dB, it is considered as osteopenia. At each level of BMD, the risk of fractures increases with age and affects other factors, such as corticosteroid use.
Maximum mass and weight gain are obtained in the third trimester. Afterwards, absorption and bone formation processes become unbalanced and bone absorption builds. Bone loss may be due to increased activity of osteoclasts and decreased osteoblastic activity.
Reduced mass and increased risk of fracture occur as follows:
• failure to Peak Bone Mass ultimate
• Increase Bone Absorption
• Reduce Bone formation
is based on studies on twins to about 85% of the maximum Bone mass determined by genetics. In addition to genetic activity, environmental factors such as nutrition (calcium vitamin D) and physical activity are also important in maximizing the mass and cytotoxicity.
As the age increases, osteoporosis often occurs, as the prostate tissue is progressively lost, and the number of fractures increases gradually. Reducing mass and weight in men before menopause and in men from decades to fifth. Discontinuation of ovarian function in women (menopause) results in rapid loss of mass and lacrimation, so that most women have osteoporosis criteria until the age of 70-80. In a study of the risk of hip, lumbar and hip fractures after 50 years of age, I am at 50% and in men is 13%.
The number of septal fractures is greater than the number of pelvic fractures, but because they are asymptomatic, they are usually not detected, and they are diagnosed with radiographs for other reasons.
Eating food is one of the most important factors in the bone marrow. As much as getting inadequate nutrition, the risk of bone loss and osteoporosis increases. Bone formation requires sufficient amounts of calcium, protein, magnesium, phosphorus, vitamin D , potassium and fluoride, although minerals and other vitamins are needed for metabolic bone processes, including manganese, copper, bromine, iron, zinc And vitamins C, K, A and B. The serum normal values for each of these foods that affect the metabolism of the lozenge may not be indicative of the actual need for bone to receive the substance, and more serum levels are needed to prevent osteoporosis. According to a study, the risk of micronutrient malnutrition in the gut after menopause is high. To prevent early onset of osteoporosis after menopause, dietary interventions may be the first choice.
In most cases, calcium and vitamin D are considered as essential components of osteoporosis. Magnesium plays a role in many things, such as bone formation, preservation and regeneration. Flora has osteogenic effects, although its large amounts reduce bone strength. Bourgeois in cases of vitamin D deficiency, Magnesium and potassium play a major role, and vitamin K is also important for the activation of calcitonin.
Epidemiologic studies showed that the prevalence of cardiovascular disease, osteoporosis and type 2 diabetes in women after menopause was higher than that of young men. Micro-nutrients are involved in the production, activity and regulation of hormones, on the contrary, hormones also interfere with the metabolism of micronutrients.
The risk of nutritional disturbances, especially of the micronutrient and vitamin deficiencies, is high during menopause. The presence of micronutrients in the completion and maintenance of skeletal structures relates to the catalytic activity of these elements in the development of bone matrix.
Micro-nutrients are essential for the growth and development of bones in humans and humans. Although they form small structural components of the bones and bones, these micronutrients are very important in metabolic and bone remodeling.
Because magnesium is needed for bone growth, due to the lack of it, it is known as a risk factor for osteoporosis. Getting insufficient magnesium in humans also reduces thrombosis.
Magnesium in women during and after menopause is a predictor of tracheal intakes in the armpit and the mass of calcium in addition to calcium is also influenced by other nutritional factors. Reduction of serum magnesium, with various mechanisms including decreased parathyroid hormone secretion, resistance to the effect of this hormone, and decreased serum 1 -OH (Vitamin D) 25Causing hypocalcemia, which ultimately leads to osteoporosis .
Elderly people can potentially be at increased risk of developing magnesium deficiency. Because the absorption of this substance decreases with increasing age and, on the other hand, excretion of magnesium from the kidneys also increases. It is also possible that the elderly will use drugs such as antibiotics or diuretics, which will result in further excretion of the blood from the kidneys. However, so far, no research has been done to suggest the use of magnesium supplements to prevent bone loss or reduce fracture risk. Micronutrients such as magnesium and zinc are essential for the synthesis of bone mineral matrix.
Magnesium deficiency (Mg) It may play a role in the development of osteoporosis in postmenopausal women. In subsequent studies, it was found that eating magnesium supplements may reduce fractures and increase bone mass.
Zinc (Zn) is one of the components of the Hydroxyapatite mineral crystals in the bone, and also plays a role in regulating calcitonin secretion from the thyroid gland and therefore in bone regeneration. Zinc is essential for the proper functioning of the alkaline phosphatase enzyme (which is used to bone mineralization, the process in which hydroxyapatite crystals bind to the new bone matrix). Extreme deficiency is commonly associated with malnutrition in calories and protein, which is associated with impairment in the growth of child rearing. However, milder degrees of zinc deficiency have been reported in older people, which may potentially lead to bone loss.
There is a lot of poultry meat, meat and meat products on the meat. Cereals are also a good source for these micronutrients. There is a direct relationship between the amount of zeros and the power of readout.
The presence of copper (Cu) in collagen is necessary and may affect bone structure and also contribute to bone regeneration by suppressing the function of osteoblast and osteoclasts. The lysyl oxidaze enzyme that plays a role in the strength of collagen cores requires copper. The shortage of these micronutrients has been more noticeable in recent years. The role of copper in bone biosynthesis, connective tissue and its maintenance has been proven. However, some studies have not reported a decrease in serum copper in patients with osteoporosis. However, there are animal and human evidence that copper deficiency causes bone formation and increased fractures. Considering the presence of micronutrients and rare elements, the development and treatment of osteoporosis, it is hoped that diet plans can be considered to address all these points.